Ezkio-Itsaso (Spanish, Ezquioga-Ichaso) is a town located in the province of Guipuscoa, in the Autonomous Community of Basque Country, in northern Spain. It is a rural, idyllic place founded in 1965 by the fusion of the municipalities of Ezkio and Itsaso. Ezkio was renowned in the 1930s for the apparitions of the Virgin Mary even though the Catholic Church has not authenticated them.